Views: 7 Author: Site Editor Publish Time: 2023-12-01 Origin: Site
Friends who have used feed additives before should not be unfamiliar with mannan oligosaccharides. This type of additive has the advantages of high efficiency, environmental protection, and safe use. It can effectively increase animal weight gain and feed conversion rate, enhance resistance to diseases. So what specific physiological effects can it play?
Mannan oligosaccharides can promote the proliferation of beneficial microbial strains while inhibiting the proliferation of harmful microbial strains, and can attract pathogenic bacteria. Studies have shown that mannan oligosaccharides can adhere to the edge lectins of 11 types of Escherichia coli, block the fusion of the edge lectins of gastrointestinal pathogens with non-specific sugar molecular structures on the surface of mucosal squamous epithelial cells, prevent gastrointestinal pathogens from transplanting and breeding in the digestive tract, promote the growth and development of beneficial bacteria in the gastrointestinal tract, improve the natural environment of intestinal microbiota, and be more beneficial for human digestion and absorption.
Mannan oligosaccharides can be absorbed or immediately fused with fungal toxins to clear the harmful effects of endotoxins on the body. Experts and scholars have found that mannan oligosaccharides can fuse with gibberellin, aflatoxins, and endotoxins from Aspergillus flavus. According to research by Zaghini et al. on liquid culture media outside the body, adding yeast molds can dissolve or fuse up to 88% of Aspergillus flavus B1. Raju et al. simulated the digestive system of broiler chickens through in vitro experiments and found that the fusion rates of mannan oligosaccharides against Aspergillus flavus, gibberellin, and Aspergillus oxysporum were 82.5%, 51.6%, and 26.4%, respectively.
When there is a certain amount of MOS in the gastrointestinal tract, mannan oligosaccharides competitively bind tightly to exogenous lectins on the surface of pathogens, thereby alleviating the digestion and absorption of antigenic bodies, enhancing their potency, and improving the somatic and cellular immune responses of animals.
Shao Liangping's experiment showed that oral administration of mannan oligosaccharides can significantly increase the IgG content in serum protein of piglets (P<0.05), and significantly increase the IgA content in serum protein (P<0.01). Mannan oligosaccharides can also significantly improve the conversion rate of green plant agglutinin reticulocytes, the ability to swallow white blood cell counts, and the number of T lymphocytes in piglets (P<0.01); The levels of glutathione lactate dehydrogenase (GSH Px) and superoxide dismutase (SOD) in the blood of piglets at night were also significantly increased (P<0.01). Other research reports have also emphasized that adding mannan oligosaccharides to the diet of weaned piglets can significantly increase the content of serum protein IgG, IgA, and IgM, which are higher than those in the control experiment. It has been found that mannan oligosaccharides have a certain effect on the cellular immune system.
