Beta Glucans – the most studied immunomodulators

Studies have shown that beta glucans are potent inducers of epigenetic and functional reprogramming of innate immune cells, inducing trained immunity and long-term functional changes in monocytes and macrophages, thereby enhancing defense protection against various pathogen infections and tumor cells.

Despite the rich and diverse structure of glucans, only beta-1,3/1,6-D-glucans are classified as biological response modifiers and are immunogenic. Most of these immunogenic beta glucans are purified from fungi and yeast. Importantly, beta glucans retain their biological activity even after oral ingestion.

Yeast beta-glucan is a substance that is recognized to greatly enhance the body's natural immunity, especially for respiratory tract-related immune problems. Beta-glucan is included in the nutritional supplements recommended for the prevention and treatment of COVID-19 infection.

Can reduce the risk of upper respiratory tract infection in children

Upper respiratory tract infection is a common disease that occurs frequently in children, the elderly and athletes, especially in bad weather. The key to preventing upper respiratory tract infection is to increase the body's immunity.

A trial on yeast beta glucan and upper respiratory tract infection showed that short-term oral glucan can significantly increase the levels of albumin and lysozyme in the saliva of children with chronic respiratory diseases, thereby activating the immune function of the respiratory mucosa. Another trial also confirmed that yeast beta glucan can significantly stabilize children's IGA levels, reduce NO (nitric oxide) levels, and improve mucosal immune function.

Balance immune self-stabilization and improve allergic rhinitis symptoms

As an immunomodulator, yeast beta glucan can reduce cytokines that cause allergies. Studies have found that oral administration of a small dose of yeast beta glucan, 20 mg, for 12 weeks to patients with allergic rhinitis significantly improved symptoms.