Views: 16 Author: Site Editor Publish Time: 2023-02-23 Origin: Site
When we mention yeast, people think of active dry yeast used to make bread or steamed bread. But yeast is full of treasures. In addition to rich protein, vitamins and minerals, yeast also contains rich dietary fiber - yeast beta glucan. Yeast beta glucan is different from ordinary dietary fiber. In addition to the function of ordinary dietary fiber, it also has a strong function of enhancing immunity. It is extracted by many scientists and companies and applied to medicine and health food.
Yeast beta glucan is the main component of yeast cell wall. Together with mannan and protein, it forms the sandwich structure of yeast cell wall, which is of great significance for maintaining the size and shape of yeast cells.Yeast beta glucan is a water-insoluble branched polymer. Its main chain is beta-1,3 glycosidic binding, branched chain beta-1,6 glycoside binding, accounting for 30%~35% of the dry weight of yeast cell wall. Through electron microscopy and other analytical methods, scientists have learned about the spatial structure of yeast beta glucan. Its molecular weight ranges from tens of thousands to hundreds of thousands, and it exists in the form of triple helix.
People's interest in yeast glucan began in the 1960s. Dr. Pillemer first discovered and reported that there is a substance in yeast cell wall that can improve immunity. Later, after further research by Dr. Diluzio of Tulun University, it was found that the substance in yeast cell wall that enhances immunity is a polysaccharide— Beta-glucan, and isolate this substance from baker's yeast. Since then, research and reports on the function and application of yeast beta glucan have been emerging, and its status in people's life has also been improving. Yeast beta glucan has been certified by FDA as GRAS (generally considered safe). To obtain this certification, this substance must have no known side effects.
The immune system of humans and animals is a kind of self-protection system, which can resist the infection of foreign bacteria, viruses, tumor cells and harmful substances and damage our body. The immune system functions through some immune cells and immune factors. B cells and T cells recognize specific antigens by secreting immune factors (such as antibodies), and inactivate them by binding with antigens; Macrophages and NK cells can swallow these labeled antigens and some tumor cells.
Unlike other food ingredients, oral yeast beta glucan is not hydrolyzed by acids or enzymes in the stomach and intestines, but directly passes through the small intestine. Macrophages on small intestinal mucus cells absorb glucan through glucan receptors and then activate these cells. Beta- 1,3-glucan plays a role by stimulating macrophages, a kind of white blood cells that can play a broad role in protecting and strengthening the immune system, and protects the body from harmful substances. Macrophages are a class of major cells involved in non-specific immunity. It can devour foreign particles and destroy them. Macrophages also provide signals to other immune cells, such as B cells and T cells, to make them move to the infected place. It can also produce growth factors to repair damaged tissues.
At present, the main goal of the study of anti-cancer function is to strengthen the activity and phagocytosis of macrophages in higher mammalian tissues. One of the functions of yeast beta glucan is to enhance the ability of macrophages. In 1981, the Norwegian Cancer Research Center and Uppsala University in Sweden compared the immunity of 42 natural polysaccharides, and found that the glucan extracted from yeast and fungi can increase the phagocytic capacity of macrophages in mice by more than 10 times. In subsequent studies, it was pointed out that the immune effects of other mammals, including humans, also have the same results.
With the widespread use of antibiotics, the residue of antibiotics in animals and plants and the infection of antibiotic resistant bacteria have been increasingly concerned. A large number of clinical and subclinical trials have shown that yeast beta glucan can protect human body from a large number of gram-positive bacteria, gram-negative bacteria, antibiotic resistant bacteria, mold and parasitic bacteria. This protective function is based on the fact that yeast beta glucan can enhance the ability of the non-specific immune system to kill these infectious agents. The use of yeast glucan to fight infectious diseases such as pneumonia and Escherichia coli has achieved gratifying results.
Based on this, yeast beta glucan is widely used in feed industry, especially in aquaculture industry. A large number of studies have shown that yeast beta glucan can improve the disease resistance and growth rate of various aquatic animals such as shrimp, eel and turtle. Yao Juan and others reported that adding yeast beta glucan to the feed of Penaeus vannamei could significantly improve its immune function and disease resistance. Nuwman (1993) reported that yeast cell wall containing 2 g of glucan was added to calf feed every day. After 5 weeks of feeding, the number of Escherichia coli in feces decreased significantly, and respiratory diseases decreased from 9.9% to 3%.
Yeast beta glucan may be a good choice for those who are suffering from UV and radiation damage and are helpless. The research of the United States Air Force Radiation Biology Research Institute shows that yeast beta glucan is very helpful for the recovery of immune system and the rapid improvement of resistance after radiation. After receiving lethal dose of radiation, all mice in the control group died after two weeks, while the mortality rate of mice in the yeast beta glucan group was only 40%, and 60% of mice survived. In the process of treating tumors, radiotherapy or chemotherapy will kill a large number of white blood cells and red blood cells in the body at the same time, resulting in a decline in the ability of blood red blood cells to generate, resulting in a significant decline in the body's resistance to pathogenic bacteria. Glucans can rapidly improve the immune function of human body, and the content of white blood cells can rapidly rise to normal level.
Human body has no enzyme to digest glucan, which is difficult to digest in human digestive organs, so yeast beta glucan can play a role as dietary fiber. It can increase water holding capacity, help gastrointestinal peristalsis, and promote the excretion of harmful substances in the intestine. Yeast beta glucan also has the function of absorbing bile acid and promoting the excretion of bile acid from the body, promoting the conversion of cholesterol to bile acid, maintaining the normal metabolism of cholesterol, and effectively inhibiting the rise of cholesterol in serum.
Yeast beta glucan is widely used in food, medicine, animal feed and other fields because of its efficient functions of enhancing immunity, inhibiting harmful bacteria and dietary fiber.
In the feed additive industry, yeast glucan is widely used because it can improve the disease resistance of fish and shrimp and improve the feed conversion rate. It can be used instead of antibiotics. Moreover, yeast beta glucan can enhance animal immunity, improve animal health and disease resistance, and improve production performance by stimulating immune function and maintaining micro-ecological balance. Yeast cell walls have been widely used in the United States, Brazil and Taiwan. They have played a good role in disease prevention and treatment in livestock, poultry and aquatic products breeding, improving feed conversion rate and greatly reducing animal mortality.
In terms of health food and medicine, the United States is also ahead. The United States already has drugs with yeast beta glucan as the main substance. Because yeast beta glucan has a good role in enhancing immunity, it can rapidly improve the vitality of macrophages, which can be used to treat cancer and adjuvant treatment after radiotherapy and chemotherapy. In addition, yeast beta glucan is also used in common functional foods to play the role of dietary fiber due to its function of lowering blood lipids and cholesterol.
In the field of common food, yeast beta glucan has good water absorption function and is not digested. It is used as a fat substitute in the production of low-calorie salad dressing, cheese analogues and frozen desserts; It is used as a water-holding and oil-holding agent in most meat products such as sausage, ham and hot dog; In food, yeast beta glucan can also play a role as dietary fiber.
In addition, in the cosmetics field, yeast beta glucan can be used in shampoo, body wash, sunscreen, facial mask and other products to play its role in anti infection, anti radiation and immune enhancement, thus protecting the skin from external damage. There are many examples of application abroad.
Tessin® yeast glucan is made from high-quality Saccharomyces cerevisiae. It has white powder appearance, no pungent smell, and is 100% soluble in water. It can meet all your applications.
Chinese name: 酵母β-葡聚糖
English name: Yeast beta-glucan
CAS: 9012-72-0
Name | Parameter |
Appearanc | Off-white or light yellow powder |
Smell | Slightly characteristic odor or odorless |
PH | 6-8 |
Total bacterial count | ≤1000CFU/ |
Life time | 24 months |
Name | Parameter |
Yeast beta-glucan | ≥90% |
Protein | ≤1.0% |
Fat | ≤1.0% |
Ash | ≤3.0% |
Moistur | ≤5.0% |
1kg/aluminum foil bag, 5kg/aluminum foil bag, 20kg/carton, 25kg/drum
There are many yeast beta glucan powder factories around the world. Nanjing Tessin Biotechnology Co., Ltd is the main manufacturer of yeast beta glucan in China. Compare with other suppliers, we are the source manufacturer with a strong spot, high quality, and competitive price. The quality is close to the industry standard.